IU researchers investigate key protein in COVID-19 virus that could lead to effective new treatments
A research team at the College of Arts and Sciences at Indiana University Bloomington is uncovering important details about how the COVID-19 virus behaves inside infected cells, and their findings could help guide the development of future treatments.
A recent study published in the Journal of Biological Chemistry by Ph.D. student Patrick Laughlin, with Distinguished Professor of Molecular and Cellular Biochemistry Adam Zlotnick, focused on one of the virus’s main proteins, called the nucleocapsid protein (known as the “N-protein”), which plays a crucial role in the virus’s survival and ability to spread. Understanding how this protein works may open the door to new ways of stopping the virus in its tracks. Kimberly Young of the Zlotnick Lab, Dr. Giovanni Gonzalez-Gutierrez of the IU Electron Microscopy Center on the Bloomington campus, and Dr. Joseph Wang of Penn State University were also co-authors of the study.
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